Whereas reduced-rely MBL almost never progresses to CLL, high-count MBL progresses to CLL necessitating therapy at a amount of one% to two% per year. Large-rely MBL is distinguished from Rai 0 CLL based upon whether or not the B-mobile depend is above or beneath 5 × 109/L. Though men and women with both equally superior-depend MBL and CLL Rai phas